PDB ID: 1Y91
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Structure summary
Code : | 1Y91 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of human CDK2 complexed with a pyrazolo[1,5-a]pyrimidine inhibitor | ||||||||||||
Release Data : | 2005-02-08 | ||||||||||||
Compound : |
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Source : |
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Authors : | Williamson, D.S., Parratt, M.J., Torrance, C.J., Bower, J.F., Moore, J.D., Richardson, C.M., Dokurno, P., Cansfield, A.D., Francis, G.L., Hebdon, R.J., Howes, R., Jackson, P.S., Lockie, A.M., Murray, J.B., Nunns, C.L., Powles, J., Robertson, A., Surgenor, A.E. | ||||||||||||
Keywords : | Serine/Threonine protein kinase, CDK2, ATP-binding, Cell cycle, mitosis, phosphorylation, pyrazolopyrimidine inhibitor, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.15 Å ) | ||||||||||||
Citation : |
Structure-guided design of pyrazolo[1,5-a]pyrimidines as inhibitors of human cyclin-dependent kinase 2.
Williamson, D.S.,Parratt, M.J.,Bower, J.F.
et al.
PubMed: 15686876 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | P24941 (CDK2_HUMAN) | ||||||||||||
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