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Ligands
Code Name Style Show Link
HEM Protoporphyrin ix containing Fe
NO Nitric oxide
TRS 2-amino-2-hydroxymethyl-propane-1,3-diol
Non-standard Residues
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Glycosylation
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Code : 1Y21   PDBj   RCSB PDB   PDBe
Header : LIGAND BINDING PROTEIN
Title : Crystal Structure of Cimex Nitrophorin NO Complex
Release Data : 2004-11-30
Compound :
mol_id molecule chains
1 salivary nitrophorin A
Source :
mol_id organism_scientific organism_common expression_system
1 Cimex lectularius  (taxid:79782) Bed bug Escherichia coli BL21(DE3)  (taxid:469008)
organ: salivary glands
expression_system_strain: BL21DE3
expression_system_vector_type: plasmid
expression_system_plasmid: pET17b
Authors : Weichsel, A., Maes, E.M., Andersen, J.F., Valenzuela, J.G., Shokhireva, T.K., Walker, F.A., Montfort, W.R.
Keywords : heme protein; beta-sandwich; NO carrier; ferrous NO complex; S-nitrosocysteine, LIGAND BINDING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.75 Å )
Citation :

Heme-assisted S-nitrosation of a proximal thiolate in a nitric oxide transport protein.

Weichsel, A.,Maes, E.M.,Andersen, J.F.  et al.
(2005)  Proc.Natl.Acad.Sci.Usa  102 : 594 - 599

PubMed: 15637157
DOI: 10.1073/pnas.0406549102

Nitric Oxide Binding to Nitrophorin 4 Induces Complete Distal Pocket Burial

Weichsel, A.,Andersen, J.F.,Roberts, S.A.
(2000)  Nat.Struct.Mol.Biol.  7 : 551 - 554

Chain : A
UniProt : O76745 (NP_CIMLE)
Reaction : -