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Ligands
Code Name Style Show Link
JH0 6-(hydroxy-hexadecanoyl-amino)-2-{[(4s)-2-(2-hydroxy-phenyl)-4,5-dihydro-oxazole-4-carbonyl]-amino}-hexanoic acid 2-[(3s)-1-(tert-butyl-diphenyl-silanyloxy)-2-oxo-azepan-3-ylcarbamoyl]-(1s)-1-methyl-ethyl ester
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
FUC Alpha-L-fucopyranose
Modification
Code Name Show
Code : 1XZ0   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide
Release Data : 2005-03-01
Compound :
mol_id molecule chains synonym
1 T-cell surface glycoprotein CD1a A,C CD1a antigen, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen
mol_id molecule chains synonym
2 Beta-2-microglobulin B,D HDCMA22P
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Drosophila melanogaster  (taxid:7227)
gene: CD1A
expression_system_common: Fruit fly
expression_system_strain: S2 cells
expression_system_vector_type: plasmid
expression_system_plasmid: pRMHa3
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Drosophila melanogaster  (taxid:7227)
gene: B2M
expression_system_common: Fruit fly
expression_system_strain: S2 cells
expression_system_vector_type: plasmid
expression_system_plasmid: pRMHa3
Authors : Zajonc, D.M., Crispin, M.D., Bowden, T.A., Young, D.C., Cheng, T.Y., Hu, J., Costello, C.E., Miller, M.J., Moody, D.B., Wilson, I.A.
Keywords : beta sheet platform, MHC-fold, Protein-lipopeptide complex, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 2.80 Å )
Citation :

Molecular Mechanism of Lipopeptide Presentation by CD1a.

Zajonc, D.M.,Crispin, M.D.,Bowden, T.A.  et al.
(2005)  Immunity  22 : 209 - 219

PubMed: 15723809
DOI: 10.1016/j.immuni.2004.12.009

Chain : A, C
UniProt : P06126 (CD1A_HUMAN)
Reaction : -
Chain : B, D
UniProt : P61769 (B2MG_HUMAN)
Reaction : -