Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
CCQ L-carnitinyl-CoA inner salt
Code : 1XVV
Header : TRANSFERASE
Title : Crystal Structure of CaiB mutant D169A in complex with carnitinyl-CoA
Release Data : 2005-03-15
Compound :
mol_id molecule chains
1 Crotonobetainyl-CoA:carnitine CoA-transferase A
ec: 2.8.3.-
mutation: D169A
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli BL21  (taxid:511693)
gene: caiB
expression_system_strain: BL21
expression_system_vector_type: Plasmid
expression_system_plasmid: pGEX-4T1
Authors : Rangarajan, E.S., Li, Y., Iannuzzi, P., Cygler, M., Matte, A.
Keywords : CaiB, CoA-transferase, Carnityl-CoA, Asp mutant, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.40 Å )
Citation :

Crystal Structure of Escherichia coli Crotonobetainyl-CoA: Carnitine CoA-Transferase (CaiB) and Its Complexes with CoA and Carnitinyl-CoA.

Rangarajan, E.S.,Li, Y.,Iannuzzi, P.  et al.
(2005)  Biochemistry  44 : 5728 - 5738

PubMed: 15823031
DOI: 10.1021/bi047656f

Chain : A
UniProt : P31572 (CAIB_ECOLI)
Reaction : (E)-4-(trimethylammonio)but-2-enoyl-CoA + L- carnitine = (E)-4-(trimethylammonio)but-2-enoate + L-carnitinyl- CoA.
4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA.