Brand  (β version)

PDB ID: 1X7B

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Ligands
Code Name Style Show Link
041 2-(3-fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol PoSSuM
Non-standard Residues
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Glycosylation
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Modification
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Structure summary

Code : 1X7B   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION
Title : CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH ERB-041
Release Data : 2005-03-01
Compound :
mol_id molecule chains synonym
1 Estrogen receptor beta A,B ER-beta
mol_id molecule chains
2 STEROID RECEPTOR COACTIVATOR-1 C,D
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli BL21(DE3)  (taxid:469008)
gene: ESR2, NR3A2, ESTRB
expression_system_strain: BL21DE3
expression_system_vector_type: PLASMID
expression_system_plasmid: PET16B
mol_id organism_scientific
2
synthetic: yes
other_details: This sequence was derived from steroid receptor coactivator-1
Authors : Manas, E.S., Unwalla, R.J., Xu, Z.B., Malamas, M.S., Miller, C.P., Harris, H.A., Hsiao, C., Akopian, T., Hum, W.T., Malakian, K., Wolfrom, S., Bapat, A., Bhat, R.A., Stahl, M.L., Somers, W.S., Alvarez, J.C.
Keywords : ESTROGEN RECEPTOR, ESTROGEN RECEPTOR BETA, ER-BETA, ER, ESTROGEN, NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, AGONIST, TRANSCRIPTION
Exp. method : X-RAY DIFFRACTION ( 2.30 Å )
Citation :

Structure-Based Design of Estrogen Receptor-Beta Selective Ligands

Manas, E.S.,Unwalla, R.J.,Xu, Z.B.  et al.
(2004)  J.Am.Chem.Soc.  126 : 15106 - 15119

PubMed: 15548008
DOI: 10.1021/ja047633o

Reaction

Chain : A, B
UniProt : Q92731 (ESR2_HUMAN)
Reaction : -