Het-PDB Navi2 (PDB: 1UOU)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CMU	5-chloro-6-(1-(2-iminopyrrolidinyl) methyl) uracil				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1UOU

Code :

1UOU PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor

Release Data :

2004-01-22

Compound :

mol_id	molecule	chains	synonym
1	THYMIDINE PHOSPHORYLASE	A	TDRPASE, TP, PLATELET-DERIVED ENDOTHELIAL CELL GROWTH FACTOR, PD-ECGF, GLIOSTATIN
	ec: 2.4.2.4 fragment: RESIDUES 12-408,411-482

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:562)
	expression_system_plasmid: PMOAL-10T

Authors :

Norman, R.A., Barry, S.T., Bate, M., Breed, J., Colls, J.G., Ernill, R.J., Luke, R.W.A., Minshull, C.A., McAlister, M.S.B., McCall, E.J., McMiken, H.H.J., Paterson, D.S., Timms, D., Tucker, J.A., Pauptit, R.A.

Keywords :

PHOSPHORYLASE, TRANSFERASE, GLYCOSYLTRANSFERASE, CHEMOTAXIS, ANGIOGENESIS

Exp. method :

X-RAY DIFFRACTION ( 2.11 Å )

Citation :

Crystal Structure of Human Thymidine Phosphorylase in Complex with a Small Molecule Inhibitor

Norman, R.A.,Barry, S.T.,Bate, M. et al.
(2004) Structure 12 : 75

PubMed: 14725767
DOI: 10.1016/J.STR.2003.11.018

Chain :

UniProt :

P19971 (TYPH_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine	2.4.2.4	PubMed:1590793
	left-to-right	PubMed:1590793

PDB ID: 1UOU

Hetero Atom Contents

Structure summary

Reaction