Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
FR4 1-((1r)-1-(hydroxymethyl)-3-{6-[(3-phenylpropanoyl)amino]-1h-indol-1-yl}propyl)-1h-imidazole-4-carboxamide
ZN Zinc ion
Code : 1UML
Header : HYDROLASE
Title : Crystal structure of adenosine deaminase complexed with a potent inhibitor FR233624
Release Data : 2004-09-21
Compound :
mol_id molecule chains synonym
1 Adenosine deaminase A Adenosine aminohydrolase
ec: 3.5.4.4
Source :
mol_id organism_scientific organism_common
1 Bos taurus  (taxid:9913) Cattle
Authors : Kinoshita, T.
Keywords : beta barrel, zinc, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.5 Å )
Citation :

Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors

Terasaka, T.,Kinoshita, T.,Kuno, M.  et al.
(2004)  J.Med.Chem.  47 : 3730 - 3743

PubMed: 15239652
DOI: 10.1021/jm0306374

Chain : A
UniProt : P56658 (ADA_BOVIN)
Reaction : Adenosine + H(2)O = inosine + NH(3).