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Ligands
Code Name Style Show Link
CS8 3-thiaoctanoyl-coenzyme a
FAD Flavin-adenine dinucleotide
Non-standard Residues
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Glycosylation
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Code : 1UDY   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Medium-Chain Acyl-CoA Dehydrogenase with 3-Thiaoctanoyl-CoA
Release Data : 2003-12-09
Compound :
mol_id molecule chains synonym
1 Acyl-CoA dehydrogenase, medium-chain specific A,B,C,D MEDIUM-CHAIN ACYL-COA DEHYDROGENASE
ec: 1.3.99.3
Source :
mol_id organism_scientific organism_common
1 Sus scrofa  (taxid:9823) Pig
tissue: liver
Authors : Satoh, A., Nakajima, Y., Miyahara, I., Hirotsu, K., Tanaka, T., Nishina, Y., Shiga, K., Tamaoki, H., Setoyama, C., Miura, R.
Keywords : MCAD complex, Oxidoreductase
Exp. method : X-RAY DIFFRACTION ( 2.4 Å )
Citation :

Structure of the transition state analog of medium-chain acyl-CoA dehydrogenase. Crystallographic and molecular orbital studies on the charge-transfer complex of medium-chain acyl-CoA dehydrogenase with 3-thiaoctanoyl-CoA

Satoh, A.,Nakajima, Y.,Miyahara, I.  et al.
(2003)  J.BIOCHEM.(TOKYO)  134 : 297 - 304

PubMed: 12966080
DOI: 10.1093/jb/mvg143

Chain : A, B, C, D
UniProt : P41367 (ACADM_PIG)
Reaction: EC: Evidence:
Physiological Direction:
a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein] 1.3.8.7 PubMed:3233192
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H(+) + oxidized [electron-transfer flavoprotein] + pentanoyl- CoA = (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein] - UniProtKB:P08503
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H(+) + hexanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein] - UniProtKB:P11310
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H(+) + octanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-octenoyl-CoA + reduced [electron-transfer flavoprotein] - PubMed:3233192
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decanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-decenoyl-CoA + reduced [electron-transfer flavoprotein] - UniProtKB:P11310
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dodecanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-dodecenoyl-CoA + reduced [electron-transfer flavoprotein] - UniProtKB:P11310
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H(+) + oxidized [electron-transfer flavoprotein] + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + reduced [electron- transfer flavoprotein] - UniProtKB:P11310
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H(+) + hexadecanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-hexadecenoyl-CoA + reduced [electron-transfer flavoprotein] - UniProtKB:P11310
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