Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
FXY 1-methylheptylformamide
NAD Nicotinamide-adenine-dinucleotide
ZN Zinc ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 1U3W   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal Structure of Human Alcohol Dehydrogenase Gamma-2-Gamma-2 Isoform Complexed with N-1-Methylheptylformamide Determined to 1.45 Angstrom Resolution
Release Data : 2004-10-26
Compound :
mol_id molecule chains synonym
1 Alcohol dehydrogenase gamma chain A,B ALCOHOL DEHYDROGENASE GAMMA-2-GAMMA-2 ISOFORM
ec: 1.1.1.1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: ADH1C
expression_system_strain: DH5-alpha
expression_system_vector_type: PLASMID
expression_system_plasmid: pKK2233
Authors : Gibbons, B.J., Hurley, T.D.
Keywords : OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.45 Å )
Citation :

Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors

Gibbons, B.J.,Hurley, T.D.
(2004)  Biochemistry  43 : 12555 - 12562

PubMed: 15449945
DOI: 10.1021/bi0489107

Chain : A, B
UniProt : P00326 (ADH1G_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH 1.1.1.1 PubMed:6391957
-
ethanol + NAD(+) = acetaldehyde + H(+) + NADH 1.1.1.1 PubMed:6391957
left-to-right