Het-PDB Navi2 (PDB: 1U0X)

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Ligands
Code	Name	Link
HEM	Protoporphyrin ix containing Fe	PoSSuM
NH3	Ammonia	PoSSuM
XE	Xenon	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1U0X

Code :

1U0X PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Crystal structure of nitrophorin 4 under pressure of xenon (200 psi)

Release Data :

2004-07-20

Compound :

mol_id	molecule	chains	synonym
1	Nitrophorin 4	A	NP4

Source :

mol_id	organism_scientific	expression_system
1	Rhodnius prolixus (taxid:13249)	Escherichia coli BL21(DE3) (taxid:469008)
	expression_system_strain: BL21DE3 expression_system_vector_type: plasmid expression_system_plasmid: pET17b

Authors :

Nienhaus, K., Maes, E.M., Weichsel, A., Montfort, W.R., Nienhaus, G.U.

Keywords :

beta-barrel, lipocalin, ferric heme, xenon, Transport Protein

Exp. method :

X-RAY DIFFRACTION ( 1.45 Å )

Citation :

Structural dynamics controls nitric oxide affinity in nitrophorin 4

Nienhaus, K.,Maes, E.M.,Weichsel, A. et al.
(2004) J.Biol.Chem. 279 : 39401 - 39407

Ligand-Induced Heme Ruffling and Bent NO Geometry in Ultra-High-Resolution Structures of Nitrophorin 4

Roberts, S.A.,Weichsel, A.,Qui, Y. et al.
(2001) Biochemistry 40 : 11327 - 11337

Nitric Oxide Binding to Nitrophorin 4 Induces Complete Distal Pocket Burial

Weichsel, A.,Andersen, J.F.,Roberts, S.A. et al.
(2000) Nat.Struct.Biol. 7 : 551 - 554

Chain :

UniProt :

Q94734 (NP4_RHOPR)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
2 H(+) + 3 nitrite = H2O + nitrate + 2 nitric oxide	1.7.6.1	PubMed:20524697
2 H(+) + 3 nitrite = H2O + nitrate + 2 nitric oxide	-	PubMed:20524697

PDB ID: 1U0X