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Ligands
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SO4 Sulfate ion
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Glycosylation
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Code : 1RXT   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase.
Release Data : 2005-04-12
Compound :
mol_id molecule chains synonym
1 Glycylpeptide N-tetradecanoyltransferase 1 A,B,C,D Peptide N-myristoyltransferase 1; Myristoyl-CoA:protein N-myristoyltransferase 1; NMT 1; Type I N-myristoyltransferase
ec: 2.3.1.97
fragment: Catalytic domain
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
expression_system_vector_type: plasmid
Authors : Yang, J., Wang, Y., Frey, G., Abeles, R.H., Petsko, G.A., Ringe, D.
Keywords : alpha-beta structure; unique N-myristoyltransferase fold, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 3.0 Å )
Citation :

Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase

Yang, J.,Wang, Y.,Frey, G.  et al.
To be Published 

Chain : A, B, C, D
UniProt : P30419 (NMT1_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoylglycyl-[protein] 2.3.1.97 PubMed:22865860, PubMed:25255805, PubMed:32103017, PubMed:32111831, PubMed:32686708, PubMed:34999170, PubMed:9353336, PubMed:9506952
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N-terminal glycyl-L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein] - PubMed:32103017, PubMed:32111831
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