Brand  (β version)

PDB ID: 1Q92

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Ligands
Code Name Style Show Link
DRM {[(1r,2s)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)cyclopentyl]oxy}methylphosphonic acid PoSSuM
GOL Glycerol PoSSuM
MG Magnesium ion PoSSuM
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Structure summary

Code : 1Q92   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor PMcP-U
Release Data : 2004-04-20
Compound :
mol_id molecule chains synonym
1 5(3)-deoxyribonucleotidase A deoxyribonucleotidase
ec: 3.1.3.5
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
Authors : Rinaldo-Matthis, A., Rampazzo, C., Balzarini, J., Reichard, P., Bianchi, V., Nordlund, P.
Keywords : alpha-beta rossman fold, hydrolase
Exp. method : X-RAY DIFFRACTION ( 1.40 Å )
Citation :

Crystal structures of the mitochondrial deoxyribonucleotidase in complex with two specific inhibitors

Rinaldo-Matthis, A.,Rampazzo, C.,Balzarini, J.  et al.
(2004)  Mol.Pharmacol.  65 : 860 - 867

PubMed: 15044615
DOI: 10.1124/mol.65.4.860

Reaction

Chain : A
UniProt : Q9NPB1 (NT5M_HUMAN)
Reaction : -