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Ligands
Code Name Style Show Link
HEM Protoporphyrin ix containing Fe
SAL 2-hydroxybenzoic acid
BOG Octyl beta-D-glucopyranoside
Non-standard Residues
Code Name Show
0AH O-(bromoacetyl)-L-serine
Glycosylation
Code Name Emphasize
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
Code Name Show
Code : 1PTH   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : The Structural Basis of Aspirin Activity Inferred from the Crystal Structure of Inactivated Prostaglandin H2 Synthase
Release Data : 1996-04-11
Compound :
mol_id molecule chains synonym
1 PROSTAGLANDIN H2 SYNTHASE-1 A,B CYCLOOXYGENASE I
ec: 1.14.99.1
Source :
mol_id organism_scientific organism_common
1 Ovis aries  (taxid:9940) Sheep
organelle: SEMINAL VESICLES
Authors : Loll, P.J., Picot, D., Garavito, R.M.
Keywords : DIOXYGENASE, PEROXIDASE, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 3.4 Å )
Citation :

The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase.

Loll, P.J.,Picot, D.,Garavito, R.M.
(1995)  Nat.Struct.Biol.  2 : 637 - 643

PubMed: 7552725
DOI: 10.1038/nsb0895-637

The X-Ray Crystal Structure of the Membrane Protein Prostaglandin H2 Synthase-1

Picot, D.,Loll, P.J.,Garavito, R.M.
(1994)  Nature  367 : 243