PDB ID: 1O5M
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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336 | 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5h-benzo[5,6]cyclohepta[1,2-B]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide | PoSSuM | |||
FPP | Farnesyl diphosphate | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 1O5M
Structure summary
Code : | 1O5M PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | transferase/transferase inhibitor | ||||||||||||||||||||||||
Title : | Structure of FPT bound to the inhibitor SCH66336 | ||||||||||||||||||||||||
Release Data : | 2003-10-21 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Strickland, C.L., Weber, P.C., Ganguly, A.K. | ||||||||||||||||||||||||
Keywords : | Protein Inhibitor Complex, transferase-transferase inhibitor COMPLEX | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.3 Å ) | ||||||||||||||||||||||||
Citation : |
Tricyclic Farnesyl Protein Transferase Inhibitors: Crystallographic and Calorimetric Studies of Structure-Activity Relationships
Strickland, C.L.,Weber, P.C.,Windsor, W.T.
et al.
PubMed: 10377218 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | Q04631 (FNTA_RAT) | ||||||||||||
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Chain : | B | ||||||||
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UniProt : | Q02293 (FNTB_RAT) | ||||||||
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