Het-PDB Navi2 (PDB: 1NFB)

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Ligands
Code	Name		Style	Show	Link
CPR	6-chloropurine riboside, 5'-monophosphate				PoSSuM
NAD	Nicotinamide-adenine-dinucleotide				PoSSuM

Non-standard Residues
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Download interaction data: 1NFB

Code :

1NFB PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with 6Cl-IMP and NAD

Release Data :

2004-01-27

Compound :

mol_id	molecule	chains	synonym
1	Inosine-5'-monophosphate dehydrogenase 2	A,B	IMP dehydrogenase 2, IMPDH-II, IMPD 2
	ec: 1.1.1.205

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli BL21(DE3) (taxid:469008)
	gene: IMPDH2 expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET12B

Authors :

Risal, D., Strickler, M.D., Goldstein, B.M.

Keywords :

8 STRANDED PARALLE ALPHA/BETA BARREL, DEHYDROGENASE, IMPD, IMPDH, GUANINE NUCLEOTIDE BIOSYNTHESIS NAD, OXIDOREDUCTASE

Exp. method :

X-RAY DIFFRACTION ( 2.90 Å )

Citation :

The Conformation of NAD Bound to Human Inosine Monophosphate Dehydrogenase Type II

Risal, D.,Strickler, M.D.,Goldstein, B.M.
To be Published

Chain :

A, B

UniProt :

P12268 (IMDH2_HUMAN)

PDB ID: 1NFB