PDB ID: 1N9A
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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FTI | 1-{2-[3-(4-cyano-benzyl)-3h-imidazol-4-yl]-acetyl}-5-naphthalen-1-yl-1,2,3,6-tetrahydro-pyridine-4-carbonitrile | PoSSuM | |||
HFP | Alpha-hydroxyfarnesylphosphonic acid | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 1N9A
Structure summary
Code : | 1N9A PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE | ||||||||||||||||||||||||
Title : | Farnesyltransferase complex with tetrahydropyridine inhibitors | ||||||||||||||||||||||||
Release Data : | 2003-01-07 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Gwaltney II, S.L., O'Conner, S.J., Nelson, L.T., Sullivan, G.M., Imade, H., Wang, W., Hasvold, L., Li, Q., Cohen, J., Gu, W.Z. | ||||||||||||||||||||||||
Keywords : | Farnesyltransferase, tetrahydropyridine, Prenyltransferase, TRANSFERASE | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.20 Å ) | ||||||||||||||||||||||||
Citation : |
Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency.
Gwaltney II, S.L.,O'Connor, S.J.,Nelson, L.T.
et al.
PubMed: 12657283 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | Q04631 (FNTA_RAT) | ||||||||||||
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Chain : | B | ||||||||
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UniProt : | Q02293 (FNTB_RAT) | ||||||||
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