Het-PDB Navi2 (PDB: 1MQJ)

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Ligands
Code	Name		Style	Show	Link
HWD	2-amino-3-(2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-yl)-propionic acid				PoSSuM
ZN	Zinc ion				PoSSuM

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Download interaction data: 1MQJ

Code :

1MQJ PDBj RCSB PDB PDBe

Header :

MEMBRANE PROTEIN

Title :

Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution

Release Data :

2003-08-05

Compound :

mol_id	molecule	chains	synonym
1	glutamate receptor 2	A	GLUR-2, GLUR-B, GLUR-K2, GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2
	fragment: ligand binding core (S1S2J)

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Rattus norvegicus (taxid:10116)	Norway rat	Escherichia coli BL21(DE3) (taxid:469008)
	gene: GluR-2 or GluR-B expression_system_strain: BL21 (DE3) expression_system_vector_type: Plasmid expression_system_plasmid: PETGQ

Authors :

Jin, R., Banke, T.G., Mayer, M.L., Traynelis, S.F., Gouaux, E.

Keywords :

ionotropic glutamate receptor, GluR2, ligand binding core, S1S2, partial agonist, willardiine, MEMBRANE PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.65 Å )

Citation :

Structural basis for partial agonist action at ionotropic glutamate receptors

Jin, R.,Banke, T.G.,Mayer, M.L. et al.
(2003) Nat.Neurosci. 6 : 803 - 810

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core

Armstrong, N.,Gouaux, E.
(2000) Neuron 28 : 165 - 181

PDB ID: 1MQJ