PDB ID: 1LZQ
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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0ZQ | N-{(3s)-3-[(tert-butoxycarbonyl)amino]-4-phenylbutyl}-L-phenylalanyl-L-alpha-glutamyl-L-phenylalaninamide | PoSSuM | |||
BME | Beta-mercaptoethanol | PoSSuM |
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Download interaction data: 1LZQ
Structure summary
Code : | 1LZQ PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||
Title : | Crystal structure of the complex of mutant HIV-1 protease (A71V, V82T, I84V) with an ethylenamine peptidomimetic inhibitor BOC-PHE-PSI[CH2CH2NH]-PHE-GLU-PHE-NH2 | ||||||||||||
Release Data : | 2003-04-29 | ||||||||||||
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Authors : | Skalova, T., Hasek, J., Dohnalek, J., Petrokova, H., Buchtelova, E., Soucek, M., Majer, P., Uhlikova, T., Konvalinka, J. | ||||||||||||
Keywords : | HIV, PEPTIDOMIMETIC, ethylenamine ISOSTERE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.20 Å ) | ||||||||||||
Citation : |
An Ethylenamine Inhibitor Binds Tightly to Both Wild Type and Mutant HIV-1 Proteases. Structure and Energy Study
Skalova, T.,Hasek, J.,Dohnalek, J.
et al.
PubMed: 12699382 |
Reaction
Chain : | A, B | ||||||||||||||||||||||||
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UniProt : | P03367 (POL_HV1BR) | ||||||||||||||||||||||||
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