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Ligands
Code Name Style Show Link
FCN Fosfomycin
K Potassium ion
MN Manganese (II) ion
Non-standard Residues
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Glycosylation
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Code : 1LQP   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN (FOSA) CONTAINING BOUND SUBSTRATE
Release Data : 2002-09-11
Compound :
mol_id molecule chains synonym
1 PROBABLE FOSFOMYCIN RESISTANCE PROTEIN A,B FOSA
ec: 2.5.1.18
Source :
mol_id organism_scientific expression_system
1 Pseudomonas aeruginosa  (taxid:287) Escherichia coli BL21(DE3)  (taxid:469008)
gene: FOSA
expression_system_strain: BL21-DE3
expression_system_vector_type: PLASMID
expression_system_plasmid: PET-20
Authors : Rife, C.L., Pharris, R.E., Newcomer, M.E., Armstrong, R.N.
Keywords : potassium binding loop, manganese binding, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.19 Å )
Citation :

Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 A resolution by MAD phasing off the L-III edge of Tl(+)

Rife, C.L.,Pharris, R.E.,Newcomer, M.E.  et al.
(2002)  J.Am.Chem.Soc.  124 : 11001 - 11003

PubMed: 12224946
DOI: 10.1021/ja026879v

Chain : A, B
UniProt : Q9I4K6 (FOSA_PSEAE)
Reaction: EC: Evidence:
Physiological Direction:
glutathione + RX = a halide anion + an S-substituted glutathione + H(+) 2.5.1.18 -
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