Brand  (β version)

PDB ID: 1KGJ

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Ligands
Code Name Style Show Link
FL8 6,4'-dihydroxy-3-methyl-3',5'-dibromoflavone PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1KGJ   PDBj   RCSB PDB   PDBe
Header : TRANSPORT PROTEIN
Title : Rat transthyretin (also called prealbumin) complex with 3',5'-dibromoflavone (EMD21388)
Release Data : 2002-11-27
Compound :
mol_id molecule chains synonym
1 TRANSTHYRETIN A,B,C,D Prealbumin, TBPA
Source :
mol_id organism_scientific organism_common
1 Rattus norvegicus  (taxid:10116) Norway rat
tissue: plasma
Authors : Wojtczak, A., Neumann, P., Muziol, T., Cody, V., Luft, J.R., Pangborn, W.
Keywords : PREALBUMIN, TRANSPORT, DIBROMOFLAVONE, AURONE, THYROID HORMONE, TRANSPORT PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.30 Å )
Citation :

Comparison of binding interactions of dibromoflavonoids with transthyretin.

Muziol, T.,Cody, V.,Wojtczak, A.
(2001)  Acta Biochim.Pol.  48 : 885 - 892

PubMed: 11995999

Structural Aspects of Inotropic Bipyridine Binding. Crystal Structure Determination to 1.9 A of the Human Serum Transthyretin-Milrinone Complex

Wojtczak, A.,Luft, J.R.,Cody, V.
(1993)  J.Biol.Chem.  268 : 6202 - 6206

Mechanism of Molecular Recognition. Structural Aspects of 3,3'-Diiodo-L-Thyronine Binding to Human Serum Transthyretin

Wojtczak, A.,Luft, J.,Cody, V.
(1992)  J.Biol.Chem.  267 : 353 - 357

Structures of Human Transthyretin Complexed with Thyroxine at 2.0 A Resolution and 3',5'-Dinitro-N-Acetyl-L-Thyronine at 2.2 A Resolution

Wojtczak, A.,Cody, V.,Luft, J.R.  et al.
(1996)  Acta Crystallogr.,Sect.D  52 : 758 - 765

DOI: 10.1107/S0907444996003046

Structure of New Polymorphic Monoclinic Form of Hum Transthyretin at 3A Resolution Reveals a Mixed Comp between Unliganded and T4-Bound Tetramers of Ttr

Wojtczak, A.,Neumann, P.,Cody, V.
(2001)  Acta Crystallogr.,Sect.D  57 : 957 - 967

DOI: 10.1107/S0907444901006047

STRUCTURE OF RAT (rTTR) TRANSTHYRETIN COMPLEX WITH THYROXINE AT 2.5 A RESOLUTION: FIRST NON-BIASED INS INTO THYROXINE BINDING REVEALS DIFFERENT HORMONE ORIENTATION IN TWO BINDING SITES

Wojtczak, A.,Cody, V.,Luft, J.  et al.
(2001)  Acta Crystallogr.,Sect.D  57 : 1061 - 1070

DOI: 10.1107/S0907444901007235

Reaction

Chain : A, B, C, D
UniProt : P02767 (TTHY_RAT)
Reaction : -