Het-PDB Navi2 (PDB: 1I80)

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Ligands
Code	Name	Link
9HX	9-deazahypoxanthine	PoSSuM
IMR	Iminoribitol	PoSSuM
PO4	Phosphate ion	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1I80

Code :

1I80 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

CRYSTAL STRUCTURE OF M. TUBERCULOSIS PNP IN COMPLEX WITH IMINORIBITOL, 9-DEAZAHYPOXANTHINE AND PHOSPHATE ION

Release Data :

2001-08-01

Compound :

mol_id	molecule	chains	synonym
1	PURINE NUCLEOSIDE PHOSPHORYLASE	A,B,C	PNP, INOSINE PHOSPHORYLASE
	ec: 2.4.2.1

Source :

mol_id	organism_scientific	expression_system
1	Mycobacterium tuberculosis (taxid:1773)	Escherichia coli BL21(DE3) (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: PET-23A(+)

Authors :

Shi, W., Basso, L.A., Tyler, P.C., Furneaux, R.H., Blanchard, J.S., Almo, S.C., Schramm, V.L.

Keywords :

TRIMER, TRANSITION-STATE COMPLEX, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 2.00 Å )

Citation :

Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.

Shi, W.,Basso, L.A.,Santos, D.S. et al.
(2001) Biochemistry 40 : 8204 - 8215

PDB ID: 1I80