Het-PDB Navi2 (PDB: 1I48)

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Ligands
Code	Name		Style	Show	Link
PLP	Pyridoxal-5'-phosphate				PoSSuM
CCO	Carboxymethylthio-3-(3-chlorophenyl)-1,2,4-oxadiazol				PoSSuM

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Download interaction data: 1I48

Code :

1I48 PDBj RCSB PDB PDBe

Header :

LYASE

Title :

CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR CTCPO

Release Data :

2001-09-05

Compound :

mol_id	molecule	chains
1	CYSTATHIONINE GAMMA-SYNTHASE	A,B,C,D,E,F,G,H,I,J,K,L
	ec: 4.2.99.9

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Nicotiana tabacum (taxid:4097)	Common tobacco	Escherichia coli BL21(DE3) (taxid:469008)
	gene: METB expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: PENCN1117

Authors :

Steegborn, C., Laber, B., Messerschmidt, A., Huber, R., Clausen, T.

Keywords :

PLP-dependent enzyme, homotetramer, inhibitor complex, CTCPO, LYASE

Exp. method :

X-RAY DIFFRACTION ( 3.25 Å )

Citation :

Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.

Steegborn, C.,Laber, B.,Messerschmidt, A. et al.
(2001) J.Mol.Biol. 311 : 789 - 801

PDB ID: 1I48