PDB ID: 1HWL
Hetero Atom Contents
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ADP | Adenosine-5'-diphosphate | PoSSuM | |||
FBI | 7-[4-(4-fluoro-phenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl] -3,5-dihydroxy-heptanoic acid | PoSSuM |
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Download interaction data: 1HWL
Structure summary
Code : | 1HWL PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH ROSUVASTATIN (FORMALLY KNOWN AS ZD4522) | ||||||||||||
Release Data : | 2001-05-11 | ||||||||||||
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Authors : | Istvan, E.S., Deisenhofer, J. | ||||||||||||
Keywords : | protein-inhibitor complex, oxidoreductase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.10 Å ) | ||||||||||||
Citation : |
Structural mechanism for statin inhibition of HMG-CoA reductase.
Istvan, E.S.,Deisenhofer, J.
PubMed: 11349148 |
Reaction
Chain : | A, B, C, D | |||||||||
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UniProt : | P04035 (HMDH_HUMAN) | |||||||||
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