Het-PDB Navi2 (PDB: 1GFY)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
COL	2-(oxalyl-amino)-4,7-dihydro-5h-thieno[2,3-C]thiopyran-3-carboxylic acid				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1GFY

Code :

1GFY PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

RESIDUE 259 IS A KEY DETERMINANT OF SUBSTRATE SPECIFICITY OF PROTEIN-TYROSINE PHOSPHATASE 1B AND ALPHA

Release Data :

2000-07-04

Compound :

mol_id	molecule	chains	synonym
1	PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B)	A	PTP1B
	ec: 3.1.3.48 fragment: CATALYTIC DOMAIN mutation: R47V,D48N,M258C,G259Q

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)

Authors :

Iversen, L.F.

Keywords :

HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 2.13 Å )

Citation :

Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatases 1B and alpha.

Peters, G.H.,Iversen, L.F.,Branner, S. et al.
(2000) J.Biol.Chem. 275 : 18201 - 18209

Chain :

UniProt :

P18031 (PTN1_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate	3.1.3.48	PROSITE- ProRule:PRU10044
	-	PROSITE- ProRule:PRU10044

PDB ID: 1GFY