Het-PDB Navi2 (PDB: 1FFZ)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
PU	Puromycin-N-aminophosphonic acid

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1FFZ

Code :

1FFZ PDBj RCSB PDB PDBe

Header :

RIBOSOME

Title :

LARGE RIBOSOMAL SUBUNIT COMPLEXED WITH R(CC)-DA-PUROMYCIN

Release Data :

2000-08-28

Compound :

mol_id	molecule	chains
1	23S RIBOSOMAL RNA	A
	fragment: DOMAIN V OF 23S RIBOSOMAL RNA other_details: PART OF THE 50S LARGE RIBOSOMAL SUBUNIT

mol_id	molecule	chains
2	R(PCPC)-D(PA)-R(P*(PU))	B
	other_details: AN ANALOG OF A-SITE AMINOACYL-TRNA AND P-SITE PEPTIDYL-TRNA AS THEY ARE COVALENTLY LINKED BY THE TETRAHEDRAL CARBONYL CARBON INTERMEDIATE IN PEPTIDE BOND FORMATION. CONTAINS PU, PUROMYCIN-N-AMINOPHOSPHONIC ACID

Source :

mol_id	organism_scientific
1	Haloarcula marismortui (taxid:2238)
	other_details: CULTURED CELLS

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Nissen, P., Hansen, J., Ban, N., Moore, P.B., Steitz, T.A.

Keywords :

ribosome assembly, RNA-RNA complex, Ribozyme, ribosomal RNA, ribosome

Exp. method :

X-RAY DIFFRACTION ( 3.2 Å )

Citation :

The structural basis of ribosome activity in peptide bond synthesis.

Nissen, P.,Hansen, J.,Ban, N. et al.
(2000) Science 289 : 920 - 930

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

Ban, N.,Nissen, P.,Hansen, J. et al.
(2000) Science 289 : 905 - 920

Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit

Ban, N.,Nissen, P.,Hansen, J. et al.
(1999) Nature 400 : 841 - 847

An inhibitor of ribosomal peptidyl transferase using transition-state analogy

Welch, M.,Chastang, J.,Yarus, M.
(1995) Biochemistry 34 : 385 - 390

PDB ID: 1FFZ