Brand  (β version)

color scheme of protein:

chain: Hide other chain(s)

Modified Residues
Code Name Link
PU Puromycin-N-aminophosphonic acid
Code : 1FFZ
Header : RIBOSOME
Title : LARGE RIBOSOMAL SUBUNIT COMPLEXED WITH R(CC)-DA-PUROMYCIN
Release Data : 2000-08-28
Compound :
mol_id molecule chains
1 23S RIBOSOMAL RNA A
fragment: DOMAIN V OF 23S RIBOSOMAL RNA
other_details: PART OF THE 50S LARGE RIBOSOMAL SUBUNIT
mol_id molecule chains
2 R(P*CP*C*)-D(P*A)-R(P*(PU)) B
other_details: AN ANALOG OF A-SITE AMINOACYL-TRNA AND P-SITE PEPTIDYL-TRNA AS THEY ARE COVALENTLY LINKED BY THE TETRAHEDRAL CARBONYL CARBON INTERMEDIATE IN PEPTIDE BOND FORMATION. CONTAINS PU, PUROMYCIN-N-AMINOPHOSPHONIC ACID
Source :
mol_id organism_scientific
1 Haloarcula marismortui  (taxid:2238)
other_details: CULTURED CELLS
mol_id organism_scientific
2
synthetic: yes
Authors : Nissen, P., Hansen, J., Ban, N., Moore, P.B., Steitz, T.A.
Keywords : ribosome assembly, RNA-RNA complex, Ribozyme, ribosomal RNA, ribosome
Exp. method : X-RAY DIFFRACTION ( 3.2 Å )
Citation :

The structural basis of ribosome activity in peptide bond synthesis.

Nissen, P.,Hansen, J.,Ban, N.  et al.
(2000)  Science  289 : 920 - 930

PubMed: 10937990
DOI: 10.1126/science.289.5481.920

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

Ban, N.,Nissen, P.,Hansen, J.  et al.
(2000)  Science  289 : 905 - 920

DOI: 10.1126/science.289.5481.905

Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit

Ban, N.,Nissen, P.,Hansen, J.  et al.
(1999)  Nature  400 : 841 - 847

DOI: 10.1038/23641

An inhibitor of ribosomal peptidyl transferase using transition-state analogy

Welch, M.,Chastang, J.,Yarus, M.
(1995)  Biochemistry  34 : 385 - 390