Het-PDB Navi2 (PDB: 1F8D)

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Ligands
Code	Name		Style	Show	Link
CA	Calcium ion				PoSSuM
9AM	9-amino-2-deoxy-2,3-dehydro-N-acetyl-neuraminic acid				PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize
MAN	Alpha-D-mannopyranose
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
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Download interaction data: 1F8D

Code :

1F8D PDBj RCSB PDB PDBe

Header :

HYDROLASE/HYDROLASE INHIBITOR

Title :

Native Influenza Neuraminidase in Complex with 9-amino-2-deoxy-2,3-dehydro-N-neuraminic Acid

Release Data :

2001-04-11

Compound :

mol_id	molecule	chains
1	NEURAMINIDASE	A
	ec: 3.2.1.18 fragment: INTEGRAL MEMBRANE PROTEIN, MEMBRANE STALK CLEAVED BY PRONASE RELEASING FULLY ACTIVE RESIDUES 82-468

Source :

mol_id	organism_scientific	expression_system
1	Influenza A virus (A/tern/Australia/G70C/1975(H11N9)) (taxid:384509)	Influenza A virus (taxid:11320)
	strain: A/TERN/AUSTRALIA/G70C/75 expression_system_strain: RECOMBINANT (NWS/G70C) N9

Authors :

Smith, B.J., Colman, P.M., Von Itzstein, M., Danylec, B., Varghese, J.N.

Keywords :

neuraminidase, hydrolase, influenza protein, glycosylated protein, 9-amino-DANA, HYDROLASE-HYDROLASE INHIBITOR COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 1.40 Å )

Citation :

Analysis of inhibitor binding in influenza virus neuraminidase.

Smith, B.J.,Colman, P.M.,Von Itzstein, M. et al.
(2001) Protein Sci. 10 : 689 - 696

PDB ID: 1F8D