Brand  (β version)

PDB ID: 1DGP

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Ligands
Code Name Style Show Link
FOF (2e,6e)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol PoSSuM
FOH (2z,6z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol PoSSuM
Non-standard Residues
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Structure summary

Code : 1DGP   PDBj   RCSB PDB   PDBe
Header : LYASE
Title : ARISTOLOCHENE SYNTHASE FARNESOL COMPLEX
Release Data : 2001-02-07
Compound :
mol_id molecule chains synonym
1 ARISTOLOCHENE SYNTHASE A,B SESQUITERPENE CYCLASE, AS
ec: 4.1.99.7
Source :
mol_id organism_scientific expression_system
1 Penicillium roqueforti  (taxid:5082) Escherichia coli  (taxid:562)
expression_system_vector_type: PLASMID
expression_system_plasmid: PZW04
Authors : Caruthers, J.M., Kang, I., Cane, D.E., Christianson, D.W.
Keywords : SESQUITERPENE CYCLASE, ISOPRENOID BIOSYNTHESIS, LYASE
Exp. method : X-RAY DIFFRACTION ( 2.8 Å )
Citation :

Crystal structure determination of aristolochene synthase from the blue cheese mold, Penicillium roqueforti.

Caruthers, J.M.,Kang, I.,Rynkiewicz, M.J.  et al.
(2000)  J.Biol.Chem.  275 : 25533 - 25539

PubMed: 10825154
DOI: 10.1074/jbc.M000433200

Reaction

Chain : A, B
UniProt : Q03471 (PRX2_PENRO)
Reaction: EC: Evidence:
Physiological Direction:
(2E,6E)-farnesyl diphosphate = (+)-aristolochene + diphosphate 4.2.3.9 PubMed:15186158, PubMed:8440737
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