Brand  (β version)

PDB ID: 1DCI

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
EDO 1,2-ethanediol PoSSuM
MG Magnesium ion PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 1DCI   PDBj   RCSB PDB   PDBe
Header : LYASE
Title : DIENOYL-COA ISOMERASE
Release Data : 1999-03-30
Compound :
mol_id molecule chains synonym
1 DIENOYL-COA ISOMERASE A,B,C DELTA3,5,DELTA2,4-DIENOYL-COENZYME A ISOMERASE, PROBABLE PEROXISOMAL ENOYL-COA HYDRATASE
ec: 4.2.1.17
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Norway rat Escherichia coli  (taxid:562)
strain: WISTAR
cell_line: BL21
organ: LIVER
organelle: PEROXISOME, MITOCHONDRIA
cellular_location: PEROXISOME, MITOCHONDRIA
expression_system_strain: BL21 (DE3) LYSS
expression_system_cellular_location: CYTOPLASM
expression_system_plasmid: PET3A (NOVAGEN)
Authors : Modis, Y., Filppula, S.A., Novikov, D., Norledge, B., Hiltunen, J.K., Wierenga, R.K.
Keywords : LYASE, DIENOYL-COA ISOMERASE
Exp. method : X-RAY DIFFRACTION ( 1.5 Å )
Citation :

The crystal structure of dienoyl-CoA isomerase at 1.5 A resolution reveals the importance of aspartate and glutamate sidechains for catalysis.

Modis, Y.,Filppula, S.A.,Novikov, D.K.  et al.
(1998)  Structure  6 : 957 - 970

PubMed: 9739087
DOI: 10.1016/S0969-2126(98)00098-7

Reaction

Chain : A, B, C
UniProt : Q62651 (ECH1_RAT)
Reaction: EC: Evidence:
Physiological Direction:
(3E,5Z)-octadienoyl-CoA = (2E,4E)-octadienoyl-CoA - PubMed:11278886
-
(3E,5Z,8Z,11Z,14Z)-eicosapentaenoyl-CoA = (2E,4E,8Z,11Z,14Z)- eicosapentaenoyl-CoA - PubMed:9417087
-