Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
NF N,N'-(3,7-diazanonylene)-bis-naphthalimide
Code : 1CX3
Header : DNA
Title : SOLUTION STRUCTURE OF A COMPLEX BETWEEN D(ATGCAT)2 AND THE ANTITUMOR BISNAPHTHALIMIDE LU-79553
Release Data : 1999-11-19
Compound :
mol_id molecule chains
1 DNA (5'-D(*AP*TP*GP*CP*AP*T)-3') A,B
other_details: DNA DOUBLE HELIX INTERCALATED BY LU-79553
Source :
mol_id organism_scientific
1
synthetic: yes
Authors : Gallego, J., Reid, B.R.
Keywords : TOPOISOMERASE, ANTICANCER, DNA, NAPHTHALIMIDE, INTERCALATION, DEOXYRIBONUCLEIC ACID
Exp. method : SOLUTION NMR
Citation :

Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale.

Gallego, J.,Reid, B.R.
(1999)  Biochemistry  38 : 15104 - 15115

PubMed: 10563793
DOI: 10.1021/bi9915869