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Ligands
Code Name Style Show Link
ZN Zinc ion
CA Calcium ion
0ED N-[(1s)-3-{[(benzyloxy)carbonyl]amino}-1-carboxypropyl]-L-leucyl-N-(2-morpholin-4-ylethyl)-L-phenylalaninamide
Non-standard Residues
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Code : 1CGL   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor
Release Data : 1995-02-27
Compound :
mol_id molecule chains
1 FIBROBLAST COLLAGENASE A,B
ec: 3.4.24.7
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:469008)
cell_line: BL21(DE3)
expression_system_strain: BL21(DE3)
Authors : Lovejoy, B., Cleasby, A., Hassell, A.M., Longley, K., Luther, M.A., Weigl, D., Mcgeehan, G., Mcelroy, A.B., Drewry, D., Lambert, M.H., Jordan, S.R.
Keywords : METALLOPROTEASE, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.4 Å )
Citation :

Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor.

Lovejoy, B.,Cleasby, A.,Hassell, A.M.  et al.
(1994)  Science  263 : 375 - 377

PubMed: 8278810

Preliminary X-Ray Diffraction Studies of Recombinant 19 kDa Human Fibroblast Collagenase

Hassell, A.M.,Anderegg, R.J.,Weigl, D.  et al.
To be Published 

Metal Ion Stabilization of the Conformation of a Recombinant 19 kDa Catalytic Fragment of Human Fibroblast Collagenase

Lowry, C.L.,Mcgeehan, G.,Levine III, H.
(1992)  Proteins  12 : 42

Chain : A, B
UniProt : P00734 (THRB_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B. 3.4.21.5 -
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