Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
0GJ L-alpha-glutamyl-N-{(1s)-4-{[amino(iminio)methyl]amino}-1-[(1s)-2-chloro-1-hydroxyethyl]butyl}glycinamide
Code : 1BUI
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Structure of the ternary microplasmin-staphylokinase-microplasmin complex: a proteinase-cofactor-substrate complex in action
Release Data : 1999-09-02
Compound :
mol_id molecule chains synonym
1 Plasminogen A,B Plasmin heavy chain A, Activation peptide, Angiostatin, Plasmin heavy chain A, short form, Plasmin light chain B
ec: 3.4.21.7
fragment: Peptidase S1 catalytic domain
mol_id molecule chains synonym
2 Staphylokinase C Sak42D
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: PLG
mol_id organism_scientific
2 Staphylococcus phage 42D.m  (taxid:10715)
Authors : Parry, M.A.A., Fernandez-Catalan, C., Bergner, A., Huber, R., Hopfner, K., Schlott, B., Guehrs, K., Bode, W.
Keywords : PLASMIN, STAPHYLOKINASE, SERINE PROTEINASE, FIBRINOLYSIS, COFACTOR, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.65 Å )
Citation :

The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action.

Parry, M.A.,Fernandez-Catalan, C.,Bergner, A.  et al.
(1998)  Nat.Struct.Biol.  5 : 917 - 923

PubMed: 9783753
DOI: 10.1038/2359

Chain : A, B
UniProt : P00747 (PLMN_HUMAN)
Reaction : Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa; higher selectivity than trypsin. Converts fibrin into soluble products.
Chain : C
UniProt : P15240 (SAK_BPP42)
Reaction : -