Het-PDB Navi2 (PDB: 1BA8)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
0IT	Amino({(4s)-4-[({(3s)-3-[(benzylsulfonyl)amino]-2-oxopiperidin-1-yl}acetyl)amino]-5-oxopentyl}amino)methaniminium				PoSSuM

Non-standard Residues
Code	Name	Show
TYS	O-sulfo-L-tyrosine

Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
Code	Name	Show
ACE	Acetyl group

Download interaction data: 1BA8

Code :

1BA8 PDBj RCSB PDB PDBe

Header :

HYDROLASE/HYDROLASE INHIBITOR

Title :

THROMBIN INHIBITOR WITH A RIGID TRIPEPTIDYL ALDEHYDES

Release Data :

1999-04-27

Compound :

mol_id	molecule	chains	synonym
1	THROMBIN	A	THR-CVS1578
	ec: 3.4.21.5

mol_id	molecule	chains	synonym
2	THROMBIN	B	THR-CVS1578
	ec: 3.4.21.5

mol_id	molecule	chains
3	HIRUGEN	C

Source :

mol_id	organism_scientific	organism_common
1	Homo sapiens (taxid:9606)	Human
	tissue: BLOOD

mol_id	organism_scientific	organism_common
2	Homo sapiens (taxid:9606)	Human
	tissue: BLOOD

mol_id	organism_scientific	organism_common
3	Hirudo medicinalis (taxid:6421)	Medicinal leech

Authors :

Krishnan, R., Zhang, E., Hakansson, K., Arni, R.K., Tulinsky, A., Lim-Wilby, M.S.L., Levy, O.E., Semple, J.E., Brunck, T.K.

Keywords :

HYDROLASE-HYDROLASE INHIBITOR COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 1.8 Å )

Citation :

Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.

Krishnan, R.,Zhang, E.,Hakansson, K. et al.
(1998) Biochemistry 37 : 12094 - 12103

Chain :

UniProt :

P00734 (THRB_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
Selective cleavage of Arg-\|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.	3.4.21.5	-
	-	-

PDB ID: 1BA8