Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
UQ Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer
F3S Fe3-s4 cluster
FAD Flavin-adenine dinucleotide
FES Fe2/s2 (inorganic) cluster
GOL Glycerol
HEM Protoporphyrin ix containing Fe
JZR Hexyl beta-D-glucopyranoside
PEE 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
SF4 Iron/sulfur cluster
TEO Malate like intermediate
UNL Unknown ligand
Code : 1YQ3
Header : OXIDOREDUCTASE
Title : Avian respiratory complex II with oxaloacetate and ubiquinone
Release Data : 2005-12-20
Compound :
mol_id molecule chains synonym
1 Succinate dehydrogenase flavoprotein subunit A Fp, Flavoprotein subunit of complex II
ec: 1.3.5.1
mol_id molecule chains
2 succinate dehydrogenase Ip subunit B
ec: 1.3.5.1
mol_id molecule chains
3 SUCCINATE DEHYDROGENASE CYTOCHROME B, LARGE SUBUNIT C
ec: 1.3.5.1
mol_id molecule chains
4 SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT D
ec: 1.3.5.1
Source :
mol_id organism_scientific organism_common
1 Gallus gallus  (taxid:9031) Chicken
mol_id organism_scientific organism_common
2 Gallus gallus  (taxid:9031) Chicken
mol_id organism_scientific organism_common
3 Gallus gallus  (taxid:9031) Chicken
mol_id organism_scientific organism_common
4 Gallus gallus  (taxid:9031) Chicken
Authors : Huang, L., Cobessi, D., Tung, E.Y., Berry, E.A.
Keywords : COMPLEX II, MEMBRANE PROTEIN, HEME PROTEIN, IRON SULFUR PROTEIN, CYTOCHROME B, OXIDOREDUCTASE, REDOX ENZYME, RESPIRATORY CHAIN, OXALOACETATE UBIQUINONE
Exp. method : X-RAY DIFFRACTION ( 2.2 Å )
Citation :

3-Nitropropionic Acid Is a Suicide Inhibitor of Mitochondrial Respiration That, upon Oxidation by Complex II, Forms a Covalent Adduct with a Catalytic Base Arginine in the Active Site of the Enzyme

Huang, L.,Sun, G.,Cobessi, D.  et al.
(2006)  J.Biol.Chem.  281 : 5965 - 5972

PubMed: 16371358
DOI: 10.1074/jbc.M511270200

Crystallization of mitochondrial respiratory complex II from chicken heart: a membrane-protein complex diffracting to 2.0 A

Huang, L.S.,Borders, T.M.,Shen, J.T.  et al.
(2005)  Acta Crystallogr.,Sect.D  61 : 380 - 387

Crystal structure of mitochondrial respiratory membrane protein complex II.

Sun, F.,Huo, X.,Zhai, Y.  et al.
(2005)  Cell(Cambridge,Mass.)  121 : 1043 - 1057

Chain : A
UniProt : Q9YHT1 (SDHA_CHICK)
Reaction : Succinate + a quinone = fumarate + a quinol.
Chain : B
UniProt : Q9YHT2 (SDHB_CHICK)
Reaction : Succinate + a quinone = fumarate + a quinol.
Chain : D
UniProt : Q5ZIS0 (DHSD_CHICK)
Reaction : -