PDB ID: 1YGC
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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CA | Calcium ion | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM | |||
905 | (R)-4-[2-(3-amino-benzenesulfonylamino)-1-(3,5-diethoxy-2-fluorophenyl)-2-oxo-ethylamino]-2-hydroxy-benzamidine | PoSSuM |
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Download interaction data: 1YGC
Structure summary
Code : | 1YGC PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | HYDROLASE | ||||||||||||||||||||||||
Title : | Short Factor VIIa with a small molecule inhibitor | ||||||||||||||||||||||||
Release Data : | 2005-01-18 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Olivero, A.G., Eigenbrot, C., Goldsmith, R., Robarge, K., Artis, D.R., Flygare, J., Rawson, T., Refino, C., Bunting, S., Kirchhofer, D. | ||||||||||||||||||||||||
Keywords : | inverted oxy-anion hole, HYDROLASE | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.00 Å ) | ||||||||||||||||||||||||
Citation : |
A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo.
Olivero, A.G.,Eigenbrot, C.,Goldsmith, R.
et al.
PubMed: 15632123 |
Reaction
Chain : | L | ||||||||
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UniProt : | P08709 (FA7_HUMAN) | ||||||||
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