Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
MG Magnesium ion
CIE 2-[[[[(4-chloro-6-methoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoic acid ethyl ester
FAD Flavin-adenine dinucleotide
NHE 2-[N-cyclohexylamino]ethane sulfonic acid
P22 Ethyl dihydrogen diphosphate
Modified Residues
Code Name Link
CSD 3-sulfinoalanine
Code : 1YBH
Header : TRANSFERASE
Title : Crystal structure of Arabidopsis thaliana Acetohydroxyacid synthase In Complex With A Sulfonylurea Herbicide Chlorimuron Ethyl
Release Data : 2006-01-10
Compound :
mol_id molecule chains synonym
1 Acetolactate synthase, chloroplast A Acetohydroxy-acid synthase, ALS
ec: 2.2.1.6
fragment: Residues 86-670
Source :
mol_id organism_scientific organism_common expression_system
1 Arabidopsis thaliana  (taxid:3702) Thale cress Escherichia coli BL21(DE3)  (taxid:469008)
gene: CSR 1.2
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET30a(+)
Authors : McCourt, J.A., Pang, S.S., King-Scott, J., Guddat, L.W., Duggleby, R.G.
Keywords : Acetohydroxyacid synthase, acetolactate synthase, herbicide, sulfonylurea, thiamin diphosphate, FAD, inhibitor, cysteine-s-dioxide, CHES, transferase
Exp. method : X-RAY DIFFRACTION ( 2.50 Å )
Citation :

Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase

McCourt, J.A.,Pang, S.S.,King-Scott, J.  et al.
(2006)  Proc.Natl.Acad.Sci.Usa  103 : 569 - 573

PubMed: 16407096
DOI: 10.1073/pnas.0508701103

Chain : A
UniProt : P17597 (ILVB_ARATH)
Reaction : 2 pyruvate = 2-acetolactate + CO(2).