Het-PDB Navi2 (PDB: 1XQH)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
SAH	S-adenosyl-L-homocysteine				PoSSuM

Non-standard Residues
Code	Name	Show
MLZ	N-methyl-lysine

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1XQH

Code :

1XQH PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of a ternary complex of the methyltransferase SET9 (also known as SET7/9) with a P53 peptide and SAH

Release Data :

2004-11-23

Compound :

mol_id	molecule	chains	synonym
1	Histone-lysine N-methyltransferase, H3 lysine-4 specific	A,E	LYSINE N-METHYLTRANSFERASE, Histone H3-K4 methyltransferase, H3-K4-HMTase, SET domain- containing Set7, Set9, SET7/9
	ec: 2.1.1.43 fragment: N-domain, SET-domain

mol_id	molecule	chains
2	9-mer peptide from tumor protein p53	B,F
	fragment: mono-methylated p53 peptide

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli BL21(DE3) (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: pGEX-6P

mol_id	organism_scientific
2
	synthetic: yes other_details: This sequence occurs naturally in humans.

Authors :

Chuikov, S., Kurash, J.K., Wilson, J.R., Xiao, B., Justin, N., Ivanov, G.S., McKinney, K., Tempst, P., Prives, C., Gamblin, S.J., Barlev, N.A., Reinberg, D.

Keywords :

Set9-p53 complex, Set-domain, Lysine methylation, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 1.75 Å )

Citation :

Regulation of p53 activity through lysine methylation

Chuikov, S.,Kurash, J.K.,Wilson, J.R. et al.
(2004) Nature 432 : 353 - 360

PubMed: 15525938
DOI: 10.1038/nature03117

Chain :	B, F
UniProt :	P04637 (P53_HUMAN)
Reaction :	-

PDB ID: 1XQH

Hetero Atom Contents

Structure summary

Reaction