Het-PDB Navi2 (PDB: 1XIU)

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Ligands
Code	Name		Style	Show	Link
9CR	(9cis)-retinoic acid				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1XIU

Code :

1XIU PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION/TRANSFERASE

Title :

Crystal structure of the agonist-bound ligand-binding domain of Biomphalaria glabrata RXR

Release Data :

2005-09-13

Compound :

mol_id	molecule	chains	synonym
1	RXR-like protein	A,B	retinoid X receptor ligand-binding domain, 9-cis retinoic acid
	fragment: Ligand-binding domain (LBD)

mol_id	molecule	chains	synonym
2	Nuclear receptor coactivator 1	E,F	NCoA-1, Steroid receptor coactivator-1, SRC-1, RIP160, Hin-2 protein
	ec: 2.3.1.48

Source :

mol_id	organism_scientific	expression_system
1	Biomphalaria glabrata (taxid:6526)	Escherichia coli (taxid:562)
	gene: RXR expression_system_strain: BL21(DE3) pLysS expression_system_vector_type: plasmid expression_system_plasmid: pET28a

mol_id	organism_scientific
2
	synthetic: yes other_details: The peptide was chemically synthesized. The sequence of the peptide is derived from human SRC-1 coactivator.

Authors :

De Groot, A., De Rosny, E., Juillan-Binard, C., Ferrer, J.-L., Laudet, V., Pebay-Peroula, E., Fontecilla-Camps, J.-C., Borel, F.

Keywords :

Nuclear Receptor, Protein-Ligand complex, Retinoid Receptor, TRANSCRIPTION-TRANSFERASE COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 2.50 Å )

Citation :

Crystal Structure of a Novel Tetrameric Complex of Agonist-bound Ligand-binding Domain of Biomphalaria glabrata Retinoid X Receptor.

de Groot, A.,de Rosny, E.,Juillan-Binard, C. et al.
(2005) J.Mol.Biol. 354 : 841 - 853

PDB ID: 1XIU