Het-PDB Navi2 (PDB: 1XAN)

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Ligands
Code	Name		Style	Show	Link
FAD	Flavin-adenine dinucleotide				PoSSuM
HXP	3,6-dihydroxy-xanthene-9-propionic acid				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1XAN

Code :

1XAN PDBj RCSB PDB PDBe

Header :

GLUTATHIONE REDUCTASE

Title :

HUMAN GLUTATHIONE REDUCTASE IN COMPLEX WITH A XANTHENE INHIBITOR

Release Data :

1996-07-11

Compound :

mol_id	molecule	chains
1	GLUTATHIONE REDUCTASE	A
	ec: 1.6.4.2

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	expression_system_strain: SG5

Authors :

Savvides, S.N., Karplus, P.A.

Keywords :

OXIDOREDUCTASE, FLAVOENZYME, GLUTATHIONE REDUCATASE, GLUTATHIONE REDUCTASE

Exp. method :

X-RAY DIFFRACTION ( 2.0 Å )

Citation :

Kinetics and crystallographic analysis of human glutathione reductase in complex with a xanthene inhibitor.

Savvides, S.N.,Karplus, P.A.
(1996) J.Biol.Chem. 271 : 8101 - 8107

Chain :

UniProt :

P00390 (GSHR_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
2 glutathione + NADP(+) = glutathione disulfide + H(+) + NADPH	1.8.1.7	PubMed:17185460
	-	PubMed:17185460

PDB ID: 1XAN