Brand  (β version)

PDB ID: 1X06

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Ligands
Code Name Style Show Link
FPS S-[(2e,6e)-3,7,11-trimethyldodeca-2,6,10-trienyl] trihydrogen thiodiphosphate PoSSuM
MG Magnesium ion PoSSuM
PO4 Phosphate ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1X06   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of undecaprenyl pyrophosphate synthase in complex with Mg, IPP and Fspp
Release Data : 2005-03-22
Compound :
mol_id molecule chains synonym
1 Undecaprenyl pyrophosphate synthetase A UPP synthetase, Di-trans,poly-cis-decaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS
ec: 2.5.1.31
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:562) Escherichia coli BL21  (taxid:511693)
expression_system_strain: BL21
expression_system_vector_type: PLASMID
expression_system_plasmid: PET32
Authors : Guo, R.-T., Ko, T.-P., Chen, A.P.-C., Kuo, C.-J., Wang, A.H.-J., Liang, P.-H.
Keywords : enzyme-substrate complex, metal coordination, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.9 Å )
Citation :

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.

Guo, R.T.,Ko, T.P.,Chen, A.P.  et al.
(2005)  J.Biol.Chem.  280 : 20762 - 20774

PubMed: 15788389
DOI: 10.1074/jbc.M502121200

Reaction

Chain : A
UniProt : P60472 (UPPS_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
(2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di- trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate 2.5.1.31 -
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