Brand  (β version)

PDB ID: 1WYK

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Ligands
Code Name Style Show Link
FOR Formyl group PoSSuM
DIO 1,4-diethylene dioxide PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1WYK   PDBj   RCSB PDB   PDBe
Header : Viral protein, hydrolase
Title : SINDBIS VIRUS CAPSID PROTEIN (114-264)
Release Data : 1998-04-29
Compound :
mol_id molecule chains synonym
1 SINDBIS VIRUS CAPSID PROTEIN A,B,C,D SINDBIS VIRUS CORE PROTEIN
ec: 3.4.21.-
fragment: C-TERMINAL DOMAIN
Source :
mol_id organism_scientific expression_system
1 Sindbis virus  (taxid:11034) Escherichia coli BL21(DE3)  (taxid:469008)
strain: SA-AR 86
cell_line: BL21
gene: POTENTIAL
expression_system_strain: BL21 (DE3)
expression_system_vector: PET11A
expression_system_plasmid: BL21
Authors : Lee, S., Kuhn, R.J., Rossmann, M.G.
Keywords : COAT PROTEIN, SINDBIS, VIRUS, PROTEINASE, ALPHAVIRUS, CAPSID, DIOXANE, Viral protein, hydrolase
Exp. method : X-RAY DIFFRACTION ( 2.0 Å )
Citation :

Probing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building.

Lee, S.,Kuhn, R.J.,Rossmann, M.G.
(1998)  Proteins  33 : 311 - 317

PubMed: 9779796
DOI: 10.1002/(SICI)1097-0134(19981101)33:2<311::AID-PROT13>3.3.CO;2-L

Identification of a Protein Binding Site on the Surface of the Alphavirus Nucleocapsid and its Implication in Virus Assembly

Lee, S.,Owen, K.E.,Choi, H.K.  et al.
(1996)  Structure  4 : 531

Structure of Sindbis Virus Core Protein Reveals a Chymotrypsin-Like Serine Proteinase and the Organization of the Virion

Choi, H.K.,Tong, L.,Minor, W.  et al.
(1991)  Nature  354 : 37

Reaction

Chain : A, B, C, D
UniProt : P27285 (POLS_SINDO)
Reaction: EC: Evidence:
Physiological Direction:
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|- Ser- bond. 3.4.21.90 UniProtKB:P03315
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