Brand  (β version)

PDB ID: 1WOP

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Ligands
Code Name Style Show Link
FFO N-[4-({[(6s)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1WOP   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of T-protein of the Glycine Cleavage System
Release Data : 2004-09-07
Compound :
mol_id molecule chains synonym
1 Aminomethyltransferase A Glycine cleavage system T protein
ec: 2.1.2.10
Source :
mol_id organism_scientific expression_system
1 Thermotoga maritima  (taxid:2336) Escherichia coli  (taxid:562)
expression_system_strain: B834(DE3)
expression_system_vector_type: Plasmid
expression_system_plasmid: pET21a
Authors : Lee, H.H., Kim, D.J., Ahn, H.J., Ha, J.Y., Suh, S.W.
Keywords : Aminomethyltransferase, T-protein, folinic acid, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.00 Å )
Citation :

Crystal Structure of T-protein of the Glycine Cleavage System: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia

Lee, H.H.,Kim, D.J.,Ahn, H.J.  et al.
(2004)  J.Biol.Chem.  279 : 50514 - 50523

PubMed: 15355973
DOI: 10.1074/jbc.M409672200

Reaction

Chain : A
UniProt : Q9WY54 (GCST_THEMA)
Reaction: EC: Evidence:
Physiological Direction:
(6S)-5,6,7,8-tetrahydrofolate + N(6)-[(R)-S(8)- aminomethyldihydrolipoyl]-L-lysyl-[protein] = (6R)-5,10-methylene- 5,6,7,8-tetrahydrofolate + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NH4(+) 2.1.2.10 HAMAP-Rule:MF_00259
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