Het-PDB Navi2 (PDB: 1WN6)

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Ligands
Code	Name	Link
ARS	Arsenic	PoSSuM
BST	6-(4-amino-4-hydroxy-2-oxo-3,4-dihydro-2h-pyrimidin-1-yl)-3-[3-amino-5-(N-methyl-guanidino)-pent anoylamino]-3,6-dihydro-2h-pyran-2-carboxylic acid	PoSSuM
ZN	Zinc ion	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1WN6

Code :

1WN6 PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal Structure of Blasticidin S Deaminase (BSD) Complexed with Tetrahedral Intermediate of Blasticidin S

Release Data :

2005-10-25

Compound :

mol_id	molecule	chains
1	Blasticidin-S deaminase	A,B
	ec: 3.5.4.23

Source :

mol_id	organism_scientific	expression_system
1	Aspergillus terreus (taxid:33178)	Escherichia coli (taxid:562)
	strain: S-712 expression_system_vector_type: plasmid expression_system_plasmid: pET-12a

Authors :

Kumasaka, T., Yamamoto, M., Furuichi, M., Nakasako, M., Kimura, M., Yamaguchi, I., Ueki, T.

Keywords :

hydrolase, CYTIDINE DEAMINASE FAMILY, ZINC, TETRAMER

Exp. method :

X-RAY DIFFRACTION ( 1.80 Å )

Citation :

Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc

Kumasaka, T.,Yamamoto, M.,Furuichi, M. et al.
(2007) J.Biol.Chem. 282 : 37103 - 37111

Crystallization and preliminary X-ray diffraction studies of blasticidin S deaminase from Aspergillus terreus

Nakasako, M.,Kimura, M.,Yamaguchi, I.
(1999) Acta Crystallogr.,Sect.D 55 : 547 - 548

Chain :

A, B

UniProt :

P78986 (BSD_ASPTE)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
blasticidin S + H2O + H(+) = deaminohydroxyblasticidin S + NH4(+)	3.5.4.23	-
	-	-
Cofactor:	Evidence:	Note:
Zn(2+)	-	-

PDB ID: 1WN6