Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
FR7 1-{(1r,2s)-1-[2-(2,3,-dichlorophenyl)ethyl]-2-hydroxypropyl}-1h-imidazole-4-carboxamide
ZN Zinc ion
Code : 1V79
Header : HYDROLASE
Title : Crystal structures of adenosine deaminase complexed with potent inhibitors
Release Data : 2004-12-21
Compound :
mol_id molecule chains synonym
1 Adenosine deaminase A Adenosine aminohydrolase
ec: 3.5.4.4
Source :
mol_id organism_scientific organism_common
1 Bos taurus  (taxid:9913) Cattle
Authors : Kinoshita, T.
Keywords : beta barrel, zinc, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.5 Å )
Citation :

Structure-based design and synthesis of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors

Terasaka, T.,Okumura, H.,Tsuji, K.  et al.
(2004)  J.Med.Chem.  47 : 2728 - 2731

PubMed: 15139750
DOI: 10.1021/jm0499559

Chain : A
UniProt : P56658 (ADA_BOVIN)
Reaction : Adenosine + H(2)O = inosine + NH(3).