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Ligands
Code Name Style Show Link
CL Chloride ion
CRS M-cresol
UZ9 (2s)-2-amino-6-({(4r)-4-[(10r,13s)-10,13-dimethyl-3-oxohexadecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoyl}amino)hexanoic acid
ZN Zinc ion
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Code : 1UZ9   PDBj   RCSB PDB   PDBe
Header : INSULIN
Title : Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins.
Release Data : 2005-03-03
Compound :
mol_id molecule chains
1 INSULIN A
fragment: INSULIN A CHAIN, RESIDUES 90-110
mol_id molecule chains
2 INSULIN B
fragment: INSULIN B CHAIN, RESIDUES 25-53
other_details: PEPTIDE LINK BETWEEN B 29 SIDE CHAIN AND LITHOCHOLYL GROUP
Source :
mol_id organism_scientific organism_common
1 HOMO SAPIENS  (taxid:9606) HUMAN
synthetic: yes
mol_id organism_scientific organism_common
2 HOMO SAPIENS  (taxid:9606) HUMAN
synthetic: yes
Authors : Whittingham, J.L., Jonassen, I., Havelund, S., Roberts, S.M., Dodson, E.J., Verma, C.S., Wilkinson, A.J., Dodson, G.G.
Keywords : INSULIN, DIABETES MELLITUS, INSULIN FAMILY, HORMONE DISEASE MUTATION
Exp. method : X-RAY DIFFRACTION ( 1.60 Å )
Citation :

Crystallographic and Solution Studies of N-Lithocholyl Insulin: A New Generation of Prolonged-Acting Human Insulins

Whittingham, J.L.,Jonassen, I.,Havelund, S.  et al.
(2004)  Biochemistry  43 : 5987

PubMed: 15147182
DOI: 10.1021/BI036163S

Chain : B
UniProt : P01308 (INS_HUMAN)
Reaction : -