PDB ID: 1UTT
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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CA | Calcium ion | PoSSuM | |||
CP8 | 2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl) ethyl-4-(4'-ethoxy [1,1'-biphenyl]-4-yl)-4-oxobutanoic acid | PoSSuM | |||
HAE | Acetohydroxamic acid | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 1UTT
Structure summary
Code : | 1UTT PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Crystal Structure of MMP-12 complexed to 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl-4-(4-ethoxy[1,1-biphenyl]-4-yl)-4-oxobutanoic acid | ||||||||||||
Release Data : | 2004-12-15 | ||||||||||||
Compound : |
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Authors : | Morales, R., Perrier, S., Florent, J.M., Beltra, J., Dufour, S., De Mendez, I., Manceau, P., Tertre, A., Moreau, F., Compere, D., Dublanchet, A.C., O'Gara, M. | ||||||||||||
Keywords : | MACROPHAGE METALLOELASTASE, NON-ZINC CHELATOR, MMP-12, MMP INHIBITOR, HYDROLASE, METALLOPROTEASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.2 Å ) | ||||||||||||
Citation : |
Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12.
Morales, R.,Perrier, S.,Florent, J.M.
et al.
PubMed: 15289103 |
Reaction
Chain : | A | ||||||||
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UniProt : | P39900 (MMP12_HUMAN) | ||||||||
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