Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
CTN 4-amino-1-beta-D-ribofuranosyl-2(1h)-pyrimidinone
CIT Citric acid
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 1UEJ   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of human uridine-cytidine kinase 2 complexed with a substrate, cytidine
Release Data : 2004-05-04
Compound :
mol_id molecule chains synonym
1 Uridine-cytidine kinase 2 A,B URIDINE-CYTIDINE KINASE
ec: 2.7.1.48
fragment: residues 1-250
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli BL21  (taxid:511693)
expression_system_strain: BL21
expression_system_vector_type: PLASMID
expression_system_plasmid: pGEX-6P
Authors : Suzuki, N.N., Koizumi, K., Fukushima, M., Matsuda, A., Inagaki, F.
Keywords : ALPHA/BETA MONONUCLEOTIDE-BINDING HOLD, transferase
Exp. method : X-RAY DIFFRACTION ( 2.61 Å )
Citation :

Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase

Suzuki, N.N.,Koizumi, K.,Fukushima, M.  et al.
(2004)  STRUCTURE  12 : 751 - 764

PubMed: 15130468
DOI: 10.1016/j.str.2004.02.038

Crystallization and preliminary X-ray analysis of human uridine-cytidine kinase 2

Suzuki, N.N.,Koizumi, K.,Fukushima, M.  et al.
(2003)  ACTA CRYSTALLOGR.,SECT.D  59 : 1477 - 1478

PubMed: 12876357
DOI: 10.1107/S0907444903011533

Chain : A, B
UniProt : Q9BZX2 (UCK2_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + uridine = ADP + H(+) + UMP 2.7.1.48 PubMed:11306702, PubMed:11494055
-
ATP + cytidine = ADP + CMP + H(+) 2.7.1.48 PubMed:11306702, PubMed:11494055
-