Het-PDB Navi2 (PDB: 1U4N)

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Ligands
Code	Name		Style	Show	Link
SO4	Sulfate ion				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1U4N

Code :

1U4N PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal Structure Analysis of the M211S/R215L EST2 mutant

Release Data :

2004-10-05

Compound :

mol_id	molecule	chains
1	CARBOXYLESTERASE EST2	A
	mutation: M211S, R215L

Source :

mol_id	organism_scientific	expression_system
1	Alicyclobacillus acidocaldarius (taxid:405212)	Escherichia coli BL21(DE3) (taxid:469008)
	expression_system_strain: BL21(DE3) expression_system_vector_type: PLASMID expression_system_plasmid: PT7-7SCII

Authors :

De Simone, G., Menchise, V., Alterio, V., Mandrich, L., Rossi, M., Manco, G., Pedone, C.

Keywords :

ALPHA/BETA HYDROLASE FOLD, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 2.10 Å )

Citation :

The Crystal Structure of an EST2 Mutant Unveils Structural Insights on the H Group of the Carboxylesterase/Lipase Family.

De Simone, G.,Menchise, V.,Alterio, V. et al.
(2004) J.Mol.Biol. 343 : 137 - 146

A Snapshot of the Transition State Analogue of a Novel Thermophilic Esterase Belonging to the Subfamily of Mammalian Hormone-Sensitive Lipase

De Simone, G.,Galdiero, S.,Manco, G. et al.
(2000) J.Mol.Biol. 303 : 761 - 771

A Substrate-Induced Switch in the Reaction Mechanism of a Thermophilic Esterase: Kinetic Evidences and Structural Basis.

De Simone, G.,Mandrich, L.,Menchise, V. et al.
(2004) J.Biol.Chem. 279 : 6815 - 6823

PDB ID: 1U4N