Het-PDB Navi2 (PDB: 1TC1)

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Ligands
Code	Name		Style	Show	Link
FMB	Formycin B				PoSSuM
MES	2-(N-morpholino)-ethanesulfonic acid				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1TC1

Code :

1TC1 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

A 1.4 ANGSTROM CRYSTAL STRUCTURE FOR THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE OF TRYPANOSOMA CRUZI

Release Data :

1999-10-07

Compound :

mol_id	molecule	chains
1	PROTEIN (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE)	A,B
	ec: 2.4.2.8

Source :

mol_id	organism_scientific	expression_system
1	Trypanosoma cruzi (taxid:5693)	Escherichia coli (taxid:562)

Authors :

Focia, P.J., Craig III, S.P., Nieves-Alicea, R., Fletterick, R.J., Eakin, A.E.

Keywords :

TRANSFERASE, PHOSPHORIBOSYLTRANSFERASE, PURINE SALVAGE, NUCLEOTIDE METABOLISM

Exp. method :

X-RAY DIFFRACTION ( 1.41 Å )

Citation :

A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi.

Focia, P.J.,Craig III, S.P.,Nieves-Alicea, R. et al.
(1998) Biochemistry 37 : 15066 - 15075

Chain :

A, B

UniProt :

Q27796 (Q27796_TRYCR)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine	2.4.2.8	RuleBase:RU364099
	-	RuleBase:RU364099

PDB ID: 1TC1