Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
ADP Adenosine-5'-diphosphate
MG Magnesium ion
SO4 Sulfate ion
Modified Residues
Code Name Link
CYG 2-amino-4-(amino-3-oxo-propylsulfanylcarbonyl)-butyric acid
Code : 1T3T
Header : LIGASE
Title : Structure of Formylglycinamide synthetase
Release Data : 2004-09-14
Compound :
mol_id molecule chains synonym
1 Phosphoribosylformylglycinamidine synthase A FGAM synthase, FGAMS, Formylglycinamide ribotide amidotransferase, FGARAT, Formylglycinamide ribotide synthetase, Formylglycinamide synthetase
ec: 6.3.5.3
Source :
mol_id organism_scientific expression_system
1 Salmonella typhimurium  (taxid:602) Escherichia coli  (taxid:562)
gene: PURL, STM2565
expression_system_vector_type: plasmid
expression_system_plasmid: pEt28a
Authors : Ealick, S.E., Anand, R., Hoskin, A.A., Stubbe, J.
Keywords : PurL, FGAM synthetase, PurS, PurQ, formyl glycinamide, LIGASE
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Domain Organization of Salmonella typhimurium Formylglycinamide Ribonucleotide Amidotransferase Revealed by X-ray crystallography

Anand, R.,Hoskin, A.A.,Stubbe, J.  et al.
(2004)  Biochemistry  43 : 10328 - 10342

PubMed: 15301531
DOI: 10.1021/bi0491301

Chain : A
UniProt : P74881 (PUR4_SALTY)
Reaction : ATP + N(2)-formyl-N(1)-(5-phospho-D- ribosyl)glycinamide + L-glutamine + H(2)O = ADP + phosphate + 2- (formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate.