Het-PDB Navi2 (PDB: 1T3N)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
MG	Magnesium ion				PoSSuM
TTP	Thymidine-5'-triphosphate				PoSSuM

Non-standard Residues
Code	Name	Show
DOC	2',3'-dideoxycytidine-5'-monophosphate

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 1T3N

Code :

1T3N PDBj RCSB PDB PDBe

Header :

replication/DNA

Title :

Structure of the catalytic core of DNA polymerase Iota in complex with DNA and dTTP

Release Data :

2004-07-20

Compound :

mol_id	molecule	chains
1	Template DNA strand	T

mol_id	molecule	chains
2	Primer DNA strand	P

mol_id	molecule	chains
3	polymerase (DNA directed) iota	A,B

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

mol_id	organism_scientific	organism_common	expression_system
3	Homo sapiens (taxid:9606)	Human	Saccharomyces cerevisiae (taxid:4932)
	gene: POLI expression_system_common: Baker's yeast

Authors :

Nair, D.T., Johnson, R.E., Prakash, S., Prakash, L., Aggarwal, A.K.

Keywords :

protein, DNA, dTTP, replication-DNA COMPLEX

Exp. method :

X-RAY DIFFRACTION ( 2.3 Å )

Citation :

Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing.

Nair, D.T.,Johnson, R.E.,Prakash, S. et al.
(2004) Nature 430 : 377 - 380

PubMed: 15254543
DOI: 10.1038/nature02692

Chain :

A, B

UniProt :

Q9UNA4 (POLI_HUMAN)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)	2.7.7.7	PubMed:11013228, PubMed:11387224, PubMed:27555320
	-	PubMed:11013228, PubMed:11387224, PubMed:27555320

PDB ID: 1T3N

Hetero Atom Contents

Structure summary

Reaction